The TUC will work with London 2012 on areas such as training, equality, health and safety and fair employment standards.
It is estimates 30,000 people will be involved in building the Olympic park and during the London Olympics 103,000 temporary staff and 70,000 volunteers will be employed to help. While not legally binding, it is hoped the partnership with the TUC will help make the experience more positive for them.
Minister for the Olympics Tessa Jowell said: "I am delighted after so much hard work and commitment on the part of the TUC and London 2012 we are witnessing the formal agreement of the principles.
"They demonstrate the excellent working relationships between the unions and London 2012. Together they are working to ensure London 2012 is one of the most memorable experiences for the Games workforce."
Chairman of the Olympic Delivery Authority John Armitt said: "These overarching principles build on our existing positive agreement with construction unions covering the work to deliver the venues and infrastructure for London 2012. They further demonstrate a shared commitment not only to delivering a huge and complex project on time and to budget but also to high health and safety standards with fair employment conditions and a real employment and skills legacy."
TUC and London 2012 in partnership to ensure fair working conditions for Games workforce
The organisers of the London 2012 Olympic Games have agreed to work with the TUC to make sure the games are 'unforgettable' for those involved in building the Olympic park and employed during the event.