It found that FTSE 100 chief executives took home more pay by Wednesday this week, than the UK average salary of £26,500.
The thinktank said FTSE 100 executives are paid an average £4.3 million a year, equivalent to an hourly rate of £1,100.
While ordinary workers have seen their incomes squeezed, FTSE company bosses have seen their salaries rise by around 75% over the past decade, the High Pay Centre said.
High Pay Centre, director, Deborah Hargreaves, said: "When top bosses take home more in two and a half days than the average worker earns in a year, there is clearly something wrong with the way pay is set for both bosses and workers."
